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According to an article published in the Wall St. Journal, the drugs pergolide and cabergoline have been found to cause heart valve damage at an alarmingly high rate (4-7 times). The study was published in the New England Journal of Medicine and has renewed calls for the drugs to be discontinued. Valeant Pharmaceuticals International and Pfizer, manufacturers of the drugs, were less strong in their reaction to the latest findings. Both companies argued that the drugs should be used with caution in spite of the high rate of adverse effects caused by the drugs.

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